The DETECT study was a large, international, prospective, cross-sectional study. The analysis included more than 400 patients in over 60 sites across 18 countries. The study was carried out to develop an evidence-based screening algorithm for PAH in SSc patients.

Patient grouping and disposition

The DETECT study algorithm supports physicians in screening for PAH in SSc patients.


Selection of screening variables

From an initial 112 variables, 8 were selected based on their discriminatory ability to detect PAH. The variables were selected following univariable and multivariable analyses, and the clinical expertise of the Study Scientific Committee.



The DETECT Study